Single-player
Multi-player
PvP
Indie
Strategy
Online PvP
Custom Volume Controls
Mouse Only Option
Playable without Timed Input
Stereo Sound
Steam Cloud
Family Sharing
2025
Download Available
Steam Store
SIDE EFFECTS
File Size: 425 MB
Rating: 84% (Very Positive)
Added Date: Jul 10, 2026
Downloads: 2
A twisted trial of pill roulette for up to 4 players (solo or online). Pick your poison. Use experimental items to shift the odds. And remember: only one of you can survive.
Pre-installed Notice
This game is already pre-installed for you, meaning you do not need to run any setups or installer files. Simply extract the folder, double-click the game executable as Administrator, and play instantly!
About The Game
Up to four test subjects. One twisted medical trial. Only one leaves.
Welcome to Side Effects: a tense, turn-based medical roulette game. Each round you'll be presented with a selection of pills. Some are helpful, some are harmful, and some mean instant death. You never know what you're about to consume or what it might do to your mind or body. Winning means outlasting – AKA, outliving – your opponent across the table.
ResistEvery pill impacts your resistance. Manage it wisely: zero resistance means death.
Experiment Between rounds, you can choose from a range of experimental items and treatments that can shift the odds in your favor, from vaccines to mouth clamps.
You’re not aloneThe other patient wants to outlast you. They’ll bluff, adapt, and use everything at their disposal to keep breathing one dose longer than you.
Would you like to participate?
This trial includes: A single player mode
A multiplayer mode (2-4 Players)
15+ unique items
6 pill types to test
Welcome to Side Effects: a tense, turn-based medical roulette game. Each round you'll be presented with a selection of pills. Some are helpful, some are harmful, and some mean instant death. You never know what you're about to consume or what it might do to your mind or body. Winning means outlasting – AKA, outliving – your opponent across the table.
ResistEvery pill impacts your resistance. Manage it wisely: zero resistance means death.
Experiment Between rounds, you can choose from a range of experimental items and treatments that can shift the odds in your favor, from vaccines to mouth clamps.
You’re not aloneThe other patient wants to outlast you. They’ll bluff, adapt, and use everything at their disposal to keep breathing one dose longer than you.
Would you like to participate?
This trial includes: A single player mode
A multiplayer mode (2-4 Players)
15+ unique items
6 pill types to test
How to Install
1. Download the game using any of the mirrors above.
2. Extract the archive using WinRAR or 7-Zip.
3. Turn off your antivirus or add the extracted folder to exclusions (to prevent crack files deletion).
4. Run the game .exe file as administrator.
5. Play!
2. Extract the archive using WinRAR or 7-Zip.
3. Turn off your antivirus or add the extracted folder to exclusions (to prevent crack files deletion).
4. Run the game .exe file as administrator.
5. Play!
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System Requirements
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OS: Windows 10
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Processor: Intel Core i3
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Memory: 2 GB RAM
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Graphics: Relatively modern dedicted graphics card (Vulkan support required)
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Storage: 500 MB available space
Game Info
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Genre: Online PvP, Custom Volume Controls, Mouse Only Option, Playable without Timed Input, Stereo Sound, Steam Cloud, Family Sharing
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Developer: hirohun, Mr.Pootsley, Jaybooty, Lofar42
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Platform: PC
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Game Size: 425 MB
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Released By: Free Lives
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Version: Build 20892708
- Pre-Installed Game No Setup Needed